twelve cebus apella monkeys experimentally infected with 3 x 10 sobre 5 T. cruzi trypomastigotes Y strain, and treated with different doses of Spirogermanium and Nifurtimox during the acute phase of the infection, were subjected to hemoculture in order to test the sensitivity of this methd in comparsson to direct parasitemia through hemoconcentration. The 75 percent of positive results obtained with hemocutive shows a high sensitivity when compared with direct parasitemia, which did not yield any positive. This makes hemoculture suitable for long term evaluation of potential trypanocide drugs