In Paraguay, a high Toxoplasmosis seroprevalence rate (77 percent) has been estimated in adults. Our preliminary studies in 346 pregnant women from the department of San Pedro, showed a Toxoplasma gondii sero prevalence of 89 percent. This descriptive and cross-sectional study was developed in order to acquire more knowledge about the serological profile of pregnat women in our country. Seroprevalence of IgG and IgM T. gondiiantibodies was deterninedin 500 pregnant women at trem that attended the maternity of the Hospital de Clínicas to give birth from April to July 1991. A seroprevalence of chronic infection of 72 percent was found while no case of acute infection was detected