https://paraguay.bvsalud.org/base_bdnpar?q=&filter=indexed_database%3A%22BDNPAR%22+AND+author%3A%22Romero%2C+Fabiola%22 Tue, 18 Aug 2026 17:24:26 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1352357
Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the proliferation of CD1a+/Langerin+ histiocytic cells. The incidence in adultsis1 to 2 cases per million, a little more frequent in children. The presentationis variable, as a single lesion in an organ to a multisystemic disease with touch of vital organs. The tissues with the highest affinity are: bones, skin, lungs and pituitary and rarely thyroid. Delay in the diagnosis or in the treatment can cause a deterioration in thefunction of the affected organs. The objective of the communication is to report a case of LCH, with an even less frequent presentation, isolated formin the thyroid gland of an adult, a finding made after a total thyroidectomy, the diagnosis being made after histology.]]> 1352357 Tue, 02 Aug 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1352358
Pituitary stalk disruption syndrome is a congenital abnormality of probable genetic origin that causes hypopituitarism, which is radiologically characterized by adenohypophysis hypoplasia, ectopic neurohypophysis, and pituitary stalk disruption. It usuallypresents with short stature and adenohypophyseal hormone deficiency. The delay in diagnosis is related to high morbidity and mortality. The case of a 24-year-old woman who consulted for primary amenorrhea is reported. She had short stature and no secondary sexual characteristics, with infantile genitalia. Paraclinical examinations showed involvement of two pituitary axes. An MRI scan showed findings consistent with pituitary stalk disruption syndrome.]]> 1352358 Tue, 02 Aug 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1352359
A 32-year-old woman, asthmatic on irregular treatment with prednisone (last dose 1 month ago), Graves Basedow's disease for 3 years, restartedtreatment 3 months before(methimazole 40 mg / day).History of abortion two weeks prior to admission. She came for loss of consciousness, finding hypoglycemia. As hypoglycemia persists despite the treatment instituted and other etiological causes ruled out, the endocrinological evaluation confirms autoimmune hypoglycemia,autoantibody levelsagainst insulinandextremely high insulin.]]> 1352359 Tue, 02 Aug 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1291044
Objective: to determine the characteristics of patients diagnosed with Diabetic Foot in an emergency service. Materials and methods: a retrospective, descriptive study, based on the review of 525 medical records of patients who attended the Emergency-Adult service of the Hospital de Clínicas, Faculty of Medicine, National University of Asunción, Paraguay between the years 2015 and 2016. The following data were collected: age, sex, comorbidities, treatment, type of amputations, identification of the mechanism and place of initiation of injuries; destination of patients after emergencies and mortality. Results: The frequency of Diabetic Foot was 40% of 2718 patients with Diabetes, 60% were male, average age was 63 years (± 10), 34 (65.3%) had a history of high blood pressure, previous amputation 99 (18.9%), ischemic heart disease 56 (10.7%), stroke 21 (4%), smoking 18 (3.4%), 274 (52%) received surgical treatment, of which 199 were amputations (73%); 56% major amputations, 256 of 356 patients (72%) did not identify a traumatic cause of the injury; 270 (51%) referred to the fingers as the place of initiation of lesions. There were 336 discharges (64%) and 14 patients (2.67%) died. Conclusion: High frequency of patients with diabetic foot in the Emergency Department, which makes it urgent to establish structured programs for prevention and multidisciplinary treatment.]]> 1291044 Fri, 10 Sep 2021 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1400711
Objective: to determine the characteristicsof patients diagnosed with Diabetic Foot in an emergency service. Materials and methods: a retrospective, descriptive study, based on the review of 525 medical records of patients who attended the Emergency-Adult service of the Hospital de Clínicas, Faculty ofMedicine, National University of Asunción, Paraguay between the years 2015 and 2016. The following data were collected: age, sex, comorbidities, treatment, type of amputations, identification of the mechanism and place of initiation of injuries; destination of patients after emergencies and mortality. Results:The frequency of Diabetic Foot was 40% of 2718 patients with Diabetes, 60% were male, average age was 63 years (± 10),34 (65.3%) had a history of high blood pressure, previous amputation 99 (18.9%),ischemic heart disease 56 (10.7%), stroke 21 (4%), smoking 18 (3.4%),274 (52%) received surgical treatment, of which 199 were amputations (73%); 56% major amputations,256 of 356 patients (72%) did not identify a traumatic cause of the injury; 270 (51%) referred to the fingers as the place of initiation of lesions. There were 336 discharges (64%) and 14 patients (2.67%) died. Conclusion:High frequency of patients with diabetic foot in the Emergency Department, which makes it urgent to establish structured programs for prevention and multidisciplinary treatment.]]> 1400711 Thu, 24 Nov 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1291634
We present a case of sarcoidosis that presented adrenal involvement. A 44-year- old man was diagnosed with pulmonary and lymph node sarcoidosis based on clinical, laboratory, and pathological findings. Three years later, he presented with generalized weakness, nausea, persistent hyponatraemia, arterial hypotension, weight loss, and skin hyperpigmentation. Endocrinologic evaluation confirms primary adrenal insufficiency, suggesting infiltration of sarcoidosis into the adrenal glands.]]> 1291634 Tue, 21 Sep 2021 00:00:00 UTC