https://paraguay.bvsalud.org/base_bdnpar?q=&filter=indexed_database%3A%22BDNPAR%22+AND+author%3A%22Mereles+Aranda%2C+Eva+Fabiana%22 Thu, 14 May 2026 14:05:48 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1400136
Introduction.Meningitis is a disease that requires immediate diagnosis and treatment. The epidemiology changed over the years due to the advances in conjugate vaccines, however, the mortality rate, as well as the disease burden, are still very high. Objective.To describe the epidemiological characteristics of meningitis mortality in Paraguay in the 2015-2019 period. Materials and methods.Descriptive and ecological study in which data was obtained from the open and official website of the General Department of Strategic Information of the Ministry of Public Health and Social Welfare. Crude and adjusted rates (per 100,000 inhabitants) were calculated using Excel and EPI INFO 7.0. Results.In the study period, 125 deaths were registered with the highest prevalence in 2018 (adjusted rate of 0.55 per 100,000 inhabitants) and the lowest in 2017 (adjusted rate of 0.27 per 100,000 inhabitants). The months with the highest mortality were August and December with 15.2% and 11.2%, respectively. Males were the predominant gender with 58.40% (73 people), 21.60% (27) were under 4 years of age, mostly women, and 12% (11) were seniors (60-70 years), mostly men. Average age was 37.76 years, 67.20% single (84) and 26.40% (33)had no formal education and 80.80% (101) lived in urban areas. The highest rates were registered in Paraguarí (6.8 per 100,000 inhabitants) and Caazapa (3.3 per 100,000 inhabitants). There were no cases in Alto Paraguay. Conclusion: The extremes of life remain a vulnerable population for meningitis.]]> 1400136 Thu, 17 Nov 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1388742
ABSTRACT Introduction. The severity of patients hospitalized for COVID-19 can be determined by its sociodemographic characteristics and underlying diseases, as well as changes in symptoms and laboratory results. Objective. to analyze severity predictors in patients hospitalized for COVID-19 at the Alto Paraná Respiratory Integrated Hospital. Methodology. Observational cros-sectional, retrospective study. Clinical charts of patients hospitalized between January and March of 2021 were retrospectively reviewed. Sociodemographic and clinical characteristics and severity risk factors were analyzed. Results. Of the 137 patients studied, 62.0% (n=85) were male. Mortality was 43.8% (n=60), similar in those under and over 60 years old. ICU admission was associated with higher mortality 69.4% (n=43) (p<0.001). The main symptoms were dyspnea 63.5% (n=87), dry cough 55.47% (n=76) and fever 54.0% (n=74), only dyspnea was associated (p<0.05) to death. The most frequent underlying diseases associated with a higher risk of death (p<0.001) were arterial hypertension, diabetes mellitus and obesity. The most frequently altered laboratory parameters were leukocytosis, neutrophilia, lymphopenia, AST, D-dimer, ferritin and glycemia, but the markers associated (p<0.05) with death were lymphopenia, AST and glycemia. Conclusion. Some severity parameters were identified that contributed to the monitoring of the patient's evolution, which can be useful as predictors in the decisions of health professionals for treatment.]]> 1388742 Wed, 23 Nov 2022 00:00:00 UTC