https://paraguay.bvsalud.org/base_bdnpar?q=&filter=indexed_database%3A%22BDNPAR%22+AND+author%3A%22Galeano%2C+Sandra%22 Sat, 16 May 2026 14:19:20 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1352357
Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the proliferation of CD1a+/Langerin+ histiocytic cells. The incidence in adultsis1 to 2 cases per million, a little more frequent in children. The presentationis variable, as a single lesion in an organ to a multisystemic disease with touch of vital organs. The tissues with the highest affinity are: bones, skin, lungs and pituitary and rarely thyroid. Delay in the diagnosis or in the treatment can cause a deterioration in thefunction of the affected organs. The objective of the communication is to report a case of LCH, with an even less frequent presentation, isolated formin the thyroid gland of an adult, a finding made after a total thyroidectomy, the diagnosis being made after histology.]]> 1352357 Tue, 02 Aug 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1352359
A 32-year-old woman, asthmatic on irregular treatment with prednisone (last dose 1 month ago), Graves Basedow's disease for 3 years, restartedtreatment 3 months before(methimazole 40 mg / day).History of abortion two weeks prior to admission. She came for loss of consciousness, finding hypoglycemia. As hypoglycemia persists despite the treatment instituted and other etiological causes ruled out, the endocrinological evaluation confirms autoimmune hypoglycemia,autoantibody levelsagainst insulinandextremely high insulin.]]> 1352359 Tue, 02 Aug 2022 00:00:00 UTC https://paraguay.bvsalud.org/base_bdnpar/resource/?id=biblioref.referenceanalytic.1291634
We present a case of sarcoidosis that presented adrenal involvement. A 44-year- old man was diagnosed with pulmonary and lymph node sarcoidosis based on clinical, laboratory, and pathological findings. Three years later, he presented with generalized weakness, nausea, persistent hyponatraemia, arterial hypotension, weight loss, and skin hyperpigmentation. Endocrinologic evaluation confirms primary adrenal insufficiency, suggesting infiltration of sarcoidosis into the adrenal glands.]]> 1291634 Tue, 21 Sep 2021 00:00:00 UTC